Automation Service Engineer I/II, Oncology

The posting, as BillionToOne wrote it

A Rare Opportunity to Shape the Future of Genomics

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

We are seeking an Automation Service Engineer I/II, Oncology to provide service support to the laboratory operations team and to be responsible for troubleshooting, maintenance, and repair of laboratory equipment utilized. This position requires a candidate that is strong in root cause analysis, application support and repair of equipment commonly used in the Next Generation Sequencing workflow. The role requires a detail-oriented candidate with experience in a regulated environment, exceptional documentation (GDP) abilities and strong written and verbal communication skills. This is an onsite position in our facility in Menlo Park, CA.

Shift Schedule: Monday - Friday, or Tuesday - Saturday PM shift

Responsibilities

• Provide service, support, and troubleshooting for automated processes and instrumentation.
• Perform and coordinate maintenance work on laboratory equipment.
• Troubleshoot, conduct root cause analysis, and problem solving on lab instruments.
• Carry out Installation, Operational, and Process Qualifications on new equipment as necessary.
• Collaborate with Quality Control to ensure all documentation is completed accurately and in accordance with regulatory requirements.
• Effectively coordinate with vendors as required for equipment issues.
• Maintain equipment parts inventory and well-organized equipment records.
• Prepare documentation as needed for equipment operation and maintenance.
• Propose and design plans for process improvements.
• Represent the equipment and automation teams in cross-functional meetings.
• Undertake special projects as assigned.

Requirements

• BS degree in a scientific discipline.
• 3+ years of experience in operating and troubleshooting laboratory equipment, preferably high-throughput molecular biology equipment, especially liquid handlers
• Strong customer focused service experience.
• Ability to engage in constructive dialogue, challenge concerns and maintain transparency.
• Prof

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BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA,a breakthrough that has already transformed the lives of over half a million patients worldwide.

Our Impact

Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample.
Unity Confirm™ enables non-invasive confirmation for high-risk screening results through the capture of intact circulating fetal cells using BillionToOne’s Fetal Cell Capture™ Technology.
Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

Our Growth

From $0 to $400M+ annualized revenue run-rate in just 6 years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Our Recognition

Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified , with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.

Our Future

Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.

Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com