Senior Product Manager, Oncology

The posting, as BillionToOne wrote it

A Rare Opportunity to Shape the Future of Genomics

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

We are looking for a Senior Product Manager, Oncology to lead and manage our therapy selection product family, Northstar Select. This role will be working closely with R&D, clinical, engineering, sales, marketing, and company leadership to lead new assay development as well as existing assay enhancements. The ideal candidate has experience launching molecular diagnostic testing assays (including FDA-approved assays), is obsessed with delivering a delightful customer experience, and thrives in a fast-paced entrepreneurial environment. This role is an hybrid (onsite 3 days/week) position and reports directly to the Head of Product, Oncology.

Responsibilities

• Understand the market and design a winning product concept: As the product owner, you need to be Number 1 expert within the company about the user needs and desires, the market, and how our technology assets can solve their problems.
• Plan and execute product launch : Understand and plan for every element that touches the product launch, including the core clinical assay, the user-facing software apps, the internal workflow, regulatory and legal constraints, and requirements, and support teams focused on marketing and PR activities, etc. Work with a wide range of departments to execute on the product launch.
• End-to-end user experience : Our product is not just the genetic testing panel but the entire experience of ordering a test, sending the blood sample, and receiving the result. You are responsible for designing and delivering the most seamless and delightful user experience for the entire process, together with a UX designer and other stakeholders.
• Program management : You are responsible for getting the product to the finish line by mobilizing relevant internal and external resources. This can involve many elements of general project and program management tasks such as driving timelines, getting stakeholders to agree on a solution, sourcing external vendors, etc.
• Continu

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BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA,a breakthrough that has already transformed the lives of over half a million patients worldwide.

Our Impact

Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample.
Unity Confirm™ enables non-invasive confirmation for high-risk screening results through the capture of intact circulating fetal cells using BillionToOne’s Fetal Cell Capture™ Technology.
Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

Our Growth

From $0 to $400M+ annualized revenue run-rate in just 6 years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Our Recognition

Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified , with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.

Our Future

Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.

Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com