Senior Data & AI Engineer

The posting, as CareDx, Inc. wrote it

CareDx is a leading precision medicine diagnostics company advancing care in transplant, specialty oncology, and cell therapy. Through our innovative portfolio of molecular diagnostics, digital health solutions, AI-powered data and analytics, and patient support services, we partner with healthcare providers, patients, and biopharma organizations to help inform clinical decision-making and improve patient outcomes.

At CareDx, every employee has the opportunity to contribute to innovations that help transform patient care and improve lives.

The Senior Data and AI Engineer will serve as a senior hands-on technical owner for solutions that transform structured and unstructured data from real-world electronic medical records (EMRs) into reliable, standardized clinical data. The role will design and deliver data engineering and clinical natural language processing (NLP) pipelines to integrate, identify, and normalize diseases, diagnoses, laboratory tests and results, demographics, signs and symptoms, medications, procedures, and other information supporting clinical, scientific, and business operations.

This role combines data engineering, clinical NLP, medical terminology and ontology expertise, applied AI, OMOP data modeling, and production software engineering. The engineer will harmonize structured EMR data, interpret clinical narratives, and integrate these sources into a transplant-focused OMOP Common Data Model (CDM). Success requires sound technical judgment, strong clinical domain knowledge, close collaboration with clinicians, and ownership from data integration and validation through deployment and ongoing production support.

Responsibilities

• Own the design, implementation, testing, deployment, and maintenance of pipelines that integrate structured EMR data and process unstructured clinical narratives.
• Develop entity and relationship extraction workflows for diagnoses, symptoms, laboratory results, demographics, medications, allergies, and procedures, linking findings to relevant values, units, doses, routes, frequencies, anatomical sites, and dates.
• Normalize structured source codes and extracted clinical concepts using ICD, SNOMED CT, RxNorm, LOINC, and other appropriate terminologies; manage local codes, synonyms, abbreviations, ambiguous mappings, terminology versions, and hospital-specific language.
• Implement clinical context interpretation, including negation, uncertainty, temporality, experiencer, and treatment status. Distinguish current conditions from historical, family, hypothetical, and ruled-out findings.
• Handle clinical note structure, copied-forward content, conflicting statements, and information spanning sentences or encounters. Reconcile extracted findings with structured EMR records using defined source and time precedence rules while retaining discrepancies, source evidence, and clinical timelines.
• Build and evaluate hybrid approaches using rules, dictionaries, statistical or deep learning mod

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#LI-Remote
This is the anticipated base salary range for candidates who will work in Brisbane, California. The final salary offered to a successful candidate will be dependent on several factors that may include, but are not limited to, the type and length of experience within the job, the type and length of experience within the industry, education, etc. Base pay is one part of the Total Package that is provided to compensate and recognize employees for their work, and this role may be eligible for additional discretionary bonuses/incentives and restricted stock units. CareDx is a multi-state employer, and this salary range may not reflect positions that work in other states.

San Francisco Bay Area Roles
$145,000 — $187,000 USD

This is the anticipated base salary range in the United States. The final salary offered to a successful candidate will be dependent on several factors that may include, but are not limited to, the type and length of experience within the job, the type and length of experience within the industry, education, etc. Base pay is one part of the Total Package that is provided to compensate and recognize employees for their work, and this role may be eligible for additional discretionary bonuses/incentives and restricted stock units. CareDx is a multi-state employer, and this salary range may not reflect positions that work in other states.

Remote: US only roles
$126,000 — $158,000 USD