Senior Director, Protein Analytics & Biophysics

The posting, as Generate Biomedicines wrote it

The Role

Generate:Biomedicines is seeking a scientifically bold, highly collaborative Senior Director to lead Protein Analytics & Biophysics within our Therapeutics division. This leader will set the vision for how Generate measures the biophysical, biochemical, and interaction properties of protein therapeutics across the design-build-test-learn cycle, from conventional analytical characterization through next-generation pooled, miniaturized, and nanoscale measurement platforms.

We are looking for a field-leading biophysicist and platform builder who has not only operated best-in-class analytical and protein interaction workflows, but has also invented, scaled, or industrialized new ways to measure protein therapeutic attributes at orders-of-magnitude higher throughput and lower sample consumption. The right person will be energized by the challenge of connecting micro- and nanoscale assay innovation with Generate's AI/ML-enabled protein design engine.

This role will own the continued excellence of conventional protein analytics, developability, and protein-protein interaction technologies while building the next generation of at-scale experimental systems. The ideal candidate brings deep technical breadth, a quantitative mindset, and a clear point of view on how pooled assays, DNA/barcode-enabled readouts, synthetic biology, automation, microfluidics, advanced detection, and computational modeling can transform how protein therapeutics are evaluated.

Success in this role will require enterprise leadership: developing leaders and senior scientists, building an inclusive and high-accountability culture, partnering deeply across Protein Sciences, Prototyping, Technology, Data Sciences, Machine Learning, Biology, and CMC/Tech Ops, and translating an ambitious scientific vision into robust capabilities that improve decision quality, speed, and scale.

Here's how you will contribute

• Set and drive the multi-year scientific and organizational vision for Protein Analytics & Biophysics, aligning functional strategy with Generate's platform, portfolio, and company priorities.
• Define the next generation of biophysical, biochemical, developability, and protein-protein interaction measurement capabilities for protein therapeutics, with a particular focus on miniaturized, pooled, high-throughput, and nanoscale approaches.
• Lead the continued evolution of conventional analytical and interaction workflows, including HPLC/UPLC, LC/MS, electrophoretic, thermal stability, light scattering, plate-based, and biosensor-based platforms, ensuring rigor, reproducibility, and decision relevance.
• Build a strategy that connects conventional analytical and biosensor technologies with emerging pooled or massively multiplexed approaches, enabling Generate to measure protein attributes at scales that match the output of generative design.
• Partner with Prototyping, Technology, Automation, Data Sciences, Machine Learning, Protein Sciences, Biology, and C

[…]
pproach aims to reduce the uncertainty, time, and cost associated with developing protein-based medicines.

Founded in 2018, we are advancing a growing pipeline of clinical and preclinical programs across multiple disease areas and protein modalities. By unifying computational design and clinical development within a single operating model, we translate this approach into clinical-stage programs and are leading a shift from traditional drug discovery toward systematic drug generation.

At Generate:Biomedicines, we collaborate across disciplines in new ways to invent and innovate. We bring diverse perspectives to a shared goal of delivering better medicines to patients in need, faster, guided by our values and leadership behaviors.

Generate:Biomedicines is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies : Generate:Biomedicines does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Generate:Biomedicines or its employees is strictly prohibited unless contacted directly by the Company’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Generate:Biomedicines and the Company will not owe any referral or other fees with respect thereto.

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Compensation: The base salary range provided reflects our current estimate of what we anticipate paying for this position. Your actual base salary will be based on several factors, including job-related skills, experience, internal equity, relevant education or training, and market dynamics. In addition, you will be eligible for an annual bonus, equity compensation, and a competitive benefits package.

Per Year Salary Range
$210,000 — $290,000 USD