Associate Director, Data Architect

The posting, as Amylyx Pharmaceuticals wrote it

Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).

Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.

The Opportunity

Amylyx Pharmaceuticals is seeking a highly motivated Associate Director, Data Architecture to lead the design, implementation, and evolution of our enterprise data platform as we prepare for commercial growth and future product launches.

This individual will play a key role in building a scalable, modern data ecosystem centered on Snowflake, enabling trusted, high-quality data across Commercial, Medical Affairs, Patient Services, Finance, R&D, Quality, and Corporate functions. The role combines enterprise data architecture, solution delivery leadership, and stakeholder engagement.

The successful candidate will serve as the technical lead for enterprise data initiatives and will partner closely with business stakeholders, external vendors, managed service providers, and implementation partners to establish a robust and scalable data foundation that supports operational excellence, analytics, reporting, and AI-enabled insights.

This is a hands-on leadership role requiring both strategic vision and deep technical expertise across data architecture, integration, data engineering, data governance, and business intelligence.

Responsibilities

Enterprise Data Architecture

• Define and maintain Amylyx's enterprise data architecture roadmap and target-state data platform.
• Lead data architecture and solution design for new business domains including Commercial, Finance, HR, R&D, Quality, and Regulatory.
• Establish scalable data architecture patterns for ingestion, transformation, storage, governance, reporting, and analytics.
• Develop and maintain enterprise data models, canonical data structures, and integration standards.

Commercial Data Platform & Launch Readiness

• Lead development and expansion of Amylyx's Commercial Data Hub and enterprise data warehouse.
• Design and oversee integration of key commercial data sources including:
• CRM, Specialty Pharmacy, Specialty Distributor, Patient Services, Claims and Prescription Data, Formulary and Market Access Data, Customer Master Data, etc.
• Support commercial launch planning through delivery of high-quality, trusted data and reporting capabilities.
• Coll

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compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.

Base salary is one component of Amylyx’s total rewards package. In addition to competitive base pay, eligible employees may receive annual performance-based bonuses and equity awards, providing an opportunity to share in the company’s long-term success. Amylyx also offers a comprehensive benefits package designed to support the health, well-being, and financial security of our employees.

Estimated Pay Range
$190,000 — $206,000 USD

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Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.