Senior Manager, Data Management

The posting, as Axsome Therapeutics wrote it

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X .

About This Role

Axsome Therapeutics is seeking a Senior Manager, Clinical Data Management to lead and oversee end-to-end clinical data management activities for assigned clinical studies and programs. This role serves as the lead data manager and a subject matter expert in core Data Management processes, ensuring high-quality, timely, inspection-ready data in compliance with ICH-GCP, applicable regulatory requirements, industry standards, and company procedures. The Sr. Manager collaborates cross-functionally with key stakeholders, provides Data Management expertise and leadership throughout study execution, and is accountable for the quality and timely delivery of Data Management milestones from study start-up through database lock and archival. This role is expected to operate independently while providing mentorship to mid-level and junior team members.

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.

Job Responsibilities and Duties include, but are not limited to, the following:

• Serve as the lead Clinical Data Manager and primary Data Management point of contact for assigned studies, providing oversight of study-level Data Management activities and vendors, developing timelines, ensuring the timely execution of study activities, and driving the achievement of key deliverables and milestones.
• Act as a subject matter expert in core Data Management processes, including EDC database development, eCRF design, edit check specification development, user acceptance testing, Data Management Plan development, mid-study EDC database changes, data cleaning, external data reconciliation management (including data transfer agreements), and database lock activities.
• Oversee DM deliverables for assigned programs and provide expert leadership for the setup, configuration review, and user acceptance testing of Randomization and Trial Supply Management (RTSM). Ensure alignment with prot

[…]
t-paced environment while maintaining accountability for timelines, quality, and regulatory compliance.

• Excellent written and verbal communication skills and a collaborative, solutions-oriented leadership style. Ability to communicate technical concepts across audiences.
• Energetic and motivated self-starter with demonstrated commitment to continuous improvement, innovation, knowledge sharing, and development of team capabilities.
• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles

Salary & Benefits

The anticipated salary range for this role is $ 145,000-$160,000 . We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.