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Senior Medical Director, Clinical Development

Beeline Medicines · Hybrid · Cambridge, Massachusetts, United States · $293k–$379.5k

Posted by Beeline Medicines on their careers site · View the original posting

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Mid level

Open 110 days

Hiring? Uncertain · Open 110 days.

The posting, as Beeline Medicines wrote it

About Beeline Medicines

Beeline Medicines is a clinical‑stage biotechnology company focused on developing and delivering category-leading precision therapies to transform the lives of people living with autoimmune and inflammatory diseases. With a portfolio of potential best-in-class and first-in-disease therapeutic candidates that directly target key pathways governing dysregulated immunological and inflammatory responses, the Company is developing medicines that have the opportunity to provide durable, life-changing impact. Led by an established executive team and backed by world-class life science investors, each day Beeline Medicines is determined to bring the scientific rigor and operational excellence to get to what matters for patients – realizing a world where people with immune-mediated diseases can live life fully.

Job Summary

The Senior Medical Director, Clinical Development is a senior physician-scientist who provides strategic medical leadership for one or more clinical programs within the organization’s Inflammation & Immunology pipeline. Building on deep therapeutic area expertise and a proven track record in clinical trial execution, this role bridges hands-on clinical program leadership with broader cross-functional and organizational accountability. The Senior Medical Director serves as the primary physician lead for assigned assets, owning the clinical strategy and development plan across multiple phases, while also playing an increasingly prominent role in shaping departmental capabilities, mentoring junior physicians, and contributing to portfolio-level decision-making. This role requires the ability to work with independence and authority in a fast-paced, growth-stage biopharmaceutical environment.

Work Arrangement & Location

Hybrid - This position follows a hybrid work schedule, requiring a minimum of two (2) days on-site per week — currently designated as Tuesday and Wednesday . Additional on-site days may be required based on business needs, team priorities, or leadership direction.

Essential Duties and Responsibilities

  • Serve as the physician medical lead for assigned clinical development programs — owning the clinical development strategy, integrated development plan, and medical decision-making for pipeline assets across Phase I through Phase III development, with increasing accountability for program-level outcomes and portfolio contributions.
  • Lead the design, authorship, and review of clinical trial protocols, investigator brochures, informed consent documents, and clinical sections of regulatory submissions (IND, NDA/BLA, global filings) — ensuring scientific rigor, patient safety, and regulatory compliance across all deliverables.
  • Provide comprehensive medical oversight of ongoing clinical trials — including safety monitoring, medical monitoring, SAE assessment, protocol deviation review, and benefit-risk evaluation — in close partnership with Clinical Operations, Pharmacovigilance, and Biost

[…]
be determined based on experience, qualifications, location, and other job-related factors permitted by applicable local law. A discretionary annual bonus and long-term incentive award (e.g., equity) may be available based on individual and Company performance.

Salary Range
$293,000 — $379,500 USD

Benefits

We offer a comprehensive benefits package tailored to the country and region in which you are hired, in compliance with local laws and practices. Benefits may include, but are not limited to:

  • Competitive health and wellness coverage (structure and premiums vary by country)
  • Paid time off, public holidays, and additional leave entitlements in accordance with local requirements
  • Flexible work arrangements / hybrid schedule

Benefits vary by location and are subject to eligibility requirements, local regulations, and plan terms. Specific benefit details applicable to your country or region will be provided during the offer process.

Equal Employment Opportunity

Beeline Medicines is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, national origin, disability, age, protected veteran status, or any other characteristic protected by applicable federal, state, or local law.

Reasonable Accommodation

If you require a reasonable accommodation to participate in the application or interview process, please contact careers@beelinemedicines.com to request an accommodation. We are committed to providing equal access to all candidates.

Privacy

Upon submission of this form I understand that Beeline Medicines is based in the United States and personal data submitted in the form will be transferred and accessed in the U.S., Information about Beeline Medicines privacy practices can be found at Privacy Policy - Beeline Medicines