Senior Director, Corporate Development

The posting, as City Therapeutics wrote it

Senior Director, Corporate Development

City Therapeutics is a biotechnology company developing the next generation of RNA interference (RNAi) therapeutics to deliver meaningful and durable benefits for patients. Founded by pioneers in the RNAi field, City combines advanced RNAi trigger engineering with novel targeting technologies to expand the therapeutic potential of RNAi in and beyond the liver. Through its proprietary pipeline and strategic collaborations, City is working to bring innovative medicines to patients with significant unmet medical needs.

City Therapeutics is seeking a strategic and execution-oriented Senior Director of Corporate Development to help shape the company’s long-term growth strategy. Reporting to the Chief Operating Officer, this individual will lead the identification, evaluation, and execution of strategic opportunities that strengthen City’s platform, advance its pipeline, and create sustainable value.

This role will work closely with executive leadership to translate corporate priorities into actionable initiatives, including strategic partnerships, licensing transactions, asset or technology acquisitions, and other growth opportunities. The individual will bring strong scientific and financial judgment, transaction experience, and the ability to build alignment across functions.

The ideal candidate combines strategic perspective with hands-on execution and is comfortable moving between market analysis, financial evaluation, external negotiations, and executive-level recommendations in a growing biotechnology company.

Key Responsibilities

• Corporate Strategy and Growth Planning: Partner with the COO and executive leadership to develop and execute City’s corporate development strategy.
• Evaluate opportunities that complement City’s internal capabilities, expand its platform or pipeline, and support long-term corporate objectives.
• Contribute to strategic planning and portfolio discussions by assessing external opportunities alongside internal investment priorities.
• Monitor industry trends, competitive developments, and relevant transactions to identify opportunities and inform decision-making.
• Develop clear strategic recommendations supported by scientific, commercial, financial, and operational analysis.
• Opportunity Identification and Assessment
• Build and maintain relationships with biotechnology and pharmaceutical companies, academic institutions, investors, advisors, and other potential strategic partners.
• Identify and prioritize opportunities for licensing, collaborations, asset or technology acquisitions, and other strategic transactions.
• Assess opportunities for strategic fit, scientific differentiation, development potential, commercial value, and execution feasibility.
• Maintain a disciplined opportunity pipeline with clear evaluation criteria, milestones, and recommendations.
• Coordinate cross-functional diligence across Research, Clinical Development, Regulatory, Fina

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sation

• The base salary range provided reflects our current estimate of what we anticipate paying for this position. Your actual base salary will be based on several factors, including job-related skills, experience, internal equity, relevant education or training, and market dynamics. In addition, you will be eligible for an annual bonus, equity compensation, and a competitive benefits package. Pay range is $250,000 to $285,000.

Our Working Model: In Person, By Design

At City, we believe that science and culture thrive together, and that happens best in person. Our working model is clear: we work onsite at our Kendall Square offices five days per week. This choice reflects our belief that great science and cultures run on connection, fairness, and growth.

• Connection: Face time matters. Building an enduring biotech company is about people, science, and strategy. Working side by side sharpens ideas, accelerates feedback, and fuels innovation for patients.
• Fairness: One model for all. Every voice counts, and fairness depends on shared experience. We hold ourselves to one standard across all levels and functions.
• Growth: Learning moves faster in person. Growth comes from conversation, observation, and mentorship. We believe in developing talent, and that happens best when we are together.
• We also know that life is not always predictable. When individual needs arise, we are flexible and supportive and work together to balance home life with life at City.
• We believe diverse teams drive better science. We welcome applicants from all backgrounds and experiences who share our mission to bring transformative RNAi medicines to patients.

City Therapeutics is an Equal Opportunity and Affirmative Action employer. All qualified applicants will receive consideration without regard to race, color, religion, national origin, gender, gender identity or expression, sexual orientation, age, disability, veteran status, or any other characteristic protected by law.