FL114: Senior Research Associate, Genomics

The posting, as Flagship Pioneering, Inc. wrote it

About FL114

FL114 is an innovative, privately held biotechnology company developing our novel epigenetic editing platform to treat a variety of diseases through precise, tunable modification of gene expression . FL114 was founded by Flagship Pioneering, where companies such as Moderna Therapeutics (NASDAQ: MRNA) and Seres Therapeutics (NASDAQ: MCRB) were conceived and created. With a strong emphasis on innovation and experimental execution, FL114 cultivates a highly dynamic and entrepreneurial environment .

About the Role

FL114, Inc. is seeking an outstanding Senior Research Associate to join our Genomics team. We’re looking for a skilled, NGS-focused molecular biologist to assist in the development and advancement of our epigenetic editing programs, from early discovery research to preclinical development and beyond. The successful candidate will be an essential member of a close-knit team of experimental and computational scientists. We are looking for enthusiastic, detail oriented, adaptive, and highly motivated individuals with a passion for bringing novel medicines to patients. Applicants should be comfortable working on a fast-paced, cross-functional scientific team.

Key Responsibilities

• Execution of NGS-based functional genomics assays in a high-throughput production environment that address core R&D needs in cell state mapping and therapeutic molecular validation
• Collaborate with research teams to help develop and support fit-for-purpose NGS solutions and molecular and cellular assay technologies
• Contribute to the development and execution of specialized molecular assays

Required Skills

• 2+ years of hands-on experience performing NGS library prep for Illumina platforms
• Familiarity with ATAC-seq, RNA-seq, ChIP-seq, Methyl-Seq, and/or 10X Single-cell
• Direct experience operating Illumina instruments
• Familiarity with liquid handlers and Kingfisher automation
• Proficiency with quantification/QC platforms (Qubit, TapeStation/BioAnalyzer)
• Hands-on experience with core molecular biology techniques such as nucleic acid extraction/purification, PCR/qPCR, restriction digestion/ligation
• Comfortable troubleshooting and optimizing assays/protocols
• Experience in an industrial, drug-development environment preferred
• Experience in immunological indications preferred

About Flagship

Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond.

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized pr
[…]
work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.

The salary range for this role is $81,000 - $107,250. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. FL114 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL114's good faith estimate as of the date of publication and may be modified in the future.

Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.