Director / Senior Director, External Manufacturing Operations

The posting, as Immunome, Inc. wrote it

Company Overview

Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, supported by a leadership team with deep experience in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugates. Our pipeline includes varegacestat, an investigational gamma secretase inhibitor for which an NDA has been accepted by the U.S. FDA; IM-1021, a clinical-stage ROR1 ADC; IM-1617, a clinical-stage solid tumor ADC; and IM-3050, a clinical-stage FAP-targeted radioligand therapy. We are also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets.

Position Overview

The Director / Senior Director, External Manufacturing Operations provides strategic leadership and oversight of Immunome’s external manufacturing network to ensure supply requirements and business objectives are met. The Director leads and develops a team of external manufacturing professionals, establishes and maintains effective supplier governance, and partners closely with Technical Operations leadership and cross-functional stakeholders to drive operational performance and successful execution of clinical and commercial programs.

This role also plays a key part in developing and executing external manufacturing and supply strategies, strengthening supplier relationships, and evolving Immunome’s external manufacturing capabilities as the company’s portfolio and manufacturing network continue to grow.

Responsibilities

• Provide overall leadership for Immunome’s External Manufacturing Operations function, with responsibility for the performance, development, and effectiveness of the team overseeing CDMOs and other external service providers.
• Lead, coach, and develop a team of external manufacturing professionals. Establish clear priorities, expectations, and accountabilities; support staff development and the continued growth of organizational capabilities as the portfolio and manufacturing network expand.
• Ensure Virtual Management Teams (VMTs) are empowered and operate effectively, collaboratively, and consistently across programs. Provide leadership in resolving significant risks, delays, and competing priorities that could affect supply or key program milestones.
• Establish and maintain effective governance across the external manufacturing network. Ensure business reviews, steering committees, and executive-level meetings are conducted at appropriate frequencies and with the right level of engagement. Serve as a senior escalation point for significant operational, contractual, supply, and relationship matters.
• Develop strong cross-functional relationships internally, partnering closely with Technical Operations leadership, Legal, Finance, Regulatory, and other key stakeholders to align activities and ensure business objectives are met.
• Provide senior lead

[…]
uding deviations, investigations, change controls, CAPAs, and batch disposition activities.

• Strong executive communication, influencing, and negotiation skills, with the ability to effectively engage internal and external senior leadership. Expert knowledge of supply agreements, service agreements, statements of work, and other commercial terms relevant to external manufacturing.
• Ability to operate effectively in a fast-paced and evolving environment, manage ambiguity, and adjust priorities while maintaining focus on critical business objectives.

Washington State Pay Range
$200,087 — $295,000 USD

Join Our Experienced, Passionate Team

Working at Immunome gives you the opportunity to make a difference in the lives of cancer patients, contribute to developing best-in-class targeted cancer therapies, and work with some of the brightest and most experienced minds in antibody-drug conjugate (ADC) development.

Immunome’s office is charged with the collective excitement and passion of people working together to develop life-changing cancer medicines. Our team thrives in an innovative, collaborative environment where employees are empowered to do their best work.

Immunome also offers a comprehensive benefit program for you and your family, including:

• Medical, dental, and vision insurance coverage for employees and their dependents, including 100% company-paid medical premiums for employees
• A 401(k) with employer match
• Employer-paid life insurance, short- and long-term disability insurance, and AD&D
• Paid time off, company holidays, and a week-long winter break between Christmas and New Years.
• Paid parental leave

E/E/O

Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

E-Verify

Immunome, Inc. is a participant in E-Verify. Please review the following notices: E-Verify Participation Poster | Right to Work Poster (English) | Right to Work Poster (Spanish) .