Senior Manager, Clinical Supply Chain – Biologics

The posting, as Oruka Therapeutics wrote it

About Us

Oruka Therapeutics (Nasdaq: ORKA) is developing novel biologics designed to set a new standard for the treatment of chronic skin diseases. Oruka’s mission is to offer patients suffering from chronic skin diseases like plaque psoriasis the greatest possible freedom from their condition by achieving high rates of complete disease clearance with dosing as infrequently as once or twice per year. Oruka is advancing a proprietary portfolio of potentially best-in-class antibodies that were engineered by Paragon Therapeutics and target the core mechanisms underlying plaque psoriasis and other dermatologic and inflammatory diseases. For more information, visit www.orukatx.com

As we build our core team, we're seeking top talent in different functional areas who are not just looking for a job, but an opportunity to be part of something bigger. Someone who is passionate about making a difference and eager to contribute to establishing an engaged, inclusive, and positive company culture.

Job Title: Senior Manager, Clinical Supply Chain – Biologics

Location: Hybrid – Waltham, MA. Candidates will be required to be in-office 3 days/week.

Role Overview

We are seeking an experienced and highly motivated Senior Manager, Clinical Supply Chain to lead clinical supply activities supporting early- through late-stage global clinical trials. This individual will be responsible for the planning and execution of clinical supply strategies, including forecasting, labeling, packaging, distribution, inventory management, Interactive Response Technology (IRT) implementation and maintenance, expiry management, and supply reconciliation.

The ideal candidate thrives in a fast-paced, collaborative environment and has demonstrated experience building strong relationships across Clinical Operations, CMC, Program Management, Regulatory Affairs, Quality, and external partners. This individual will work closely with the broader Clinical Supply Chain team to establish scalable processes and best practices while supporting multiple clinical trials across the United States, Canada, and Europe.

The successful candidate will be a proactive and highly effective communicator who anticipates supply risks, develops practical solutions, and delivers results efficiently. Experience supporting global biologics programs involving vials, pre-filled syringes, temperature-controlled products, and active comparators is strongly preferred.

Key Responsibilities

• Develop and execute clinical supply strategies for multiple early- and late-stage clinical programs, including Phase 1, Phase 2, and global Phase 3 studies.
• Lead clinical supply chain activities, including demand forecasting, labeling, packaging, distribution, inventory management, IRT implementation and maintenance, expiry management, returns, reconciliation, and destruction.
• Develop and maintain comprehensive supply plans aligned with clinical enrollment projections, dosing requirements, protocol assumptions, r

[…]
l supplies presented in vials and/or pre-filled syringes.

• Demonstrated experience managing import and export activities for clinical studies conducted in the United States, Canada, and Europe.
• Strong operational and project-management skills, with experience managing multiple programs, vendors, deliverables, timelines, contracts, and budgets simultaneously.
• Experience working with IRT systems and clinical supply forecasting or inventory-management tools.
• Demonstrated ability to identify supply risks, evaluate alternatives, and communicate recommendations clearly to cross-functional stakeholders and senior leadership.
• A proactive, adaptable, organized, and strategic approach, with the ability to operate effectively in a fast-paced and evolving environment.

Compensation

• An appropriate financial package will be developed for the successful candidate to include a competitive base salary and equity, with a performance-related bonus opportunity.
• The anticipated salary range for candidates, who will work in Waltham, MA, is $161,000 to $187,000. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc. Oruka is a multi-state employer and this salary range may not reflect positions that work in other states.

We're looking forward to hearing how you can contribute to our team and mission. Join us in shaping the future of our company and making a real impact every day.
Salary Range for the Role
$161,000 — $187,000 USD

What We Offer

• A chance to be part of a vibrant startup culture where your work can directly impact bringing new medicines to patients.
• Competitive salary and benefits package.
• A supportive and inclusive team environment where everyone is encouraged to bring their authentic selves to work.
• Opportunities for professional growth and development.