Director, Clinical Systems & Data Management

The posting, as Praxis Precision Medicines, Inc. wrote it

The Opportunity

Praxis is hiring a Director, Clinical Systems & Data. You would lead the strategy, roadmap, and delivery of the clinical systems and data capabilities that support Praxis’s clinical development and study operations. This includes translating clinical priorities and study milestones into clear technology priorities, making thoughtful investment and sequencing decisions, and driving delivery with urgency and accountability.

Within IT, you will own the clinical systems and data capability while partnering closely with Clinical Operations, Data & Analytics, Quality, Regulatory, and external technology providers. The role calls for creating clarity across functions, establishing decision rights, resolving competing priorities, and ensuring the systems and data supporting our clinical programs are reliable, scalable, secure, and fit for purpose.

You will provide leadership across clinical data engineering, data platform architecture, clinical systems delivery, and related validation activities. At the same time, you’ll stay close to the technology and the work—challenging designs, troubleshooting issues, escalating when needed, and applying sound judgment to keep delivery moving.

You will also help shape how Praxis uses clinical technology and data to work better. You’ll move the organization from fragmented or static workflows toward governed, reusable data products, analytics, and practical AI-enabled tools that help teams make better decisions and work more effectively. Success will include building an operating model that scales with the organization, strengthens inspection readiness and operational resilience, and reduces dependency on individual contributors.

Primary Responsibilities

• Own the clinical systems and data strategy and roadmap; translate clinical development priorities and study milestones into sequenced investments, clear priorities, and measurable outcomes.
• Lead and develop the clinical data engineering and data platform capability, including architecture, data flows, integrations, access controls, data quality, cloud platforms, and reusable data products across clinical systems.
• Create clarity across IT and functional teams by establishing decision rights, aligning stakeholders on requirements and acceptance decisions, resolving competing demands, and driving timely decisions.
• Partner with Clinical Operations and other functional teams to improve the reliability, usability, and scalability of clinical systems and technology-enabled study workflows.
• Lead the evolution from fragmented or static workflows toward governed, reusable analytics and practical AI-enabled tools that create meaningful value for clinical teams.
• Lead system implementations, integrations, enhancements, upgrades, issue resolution, and transition to ongoing support; coordinate internal teams, vendors, and

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rapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust , Ownership , Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.

Diversity, Equity & Inclusion
Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE ® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.

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