Senior Director, Intellectual Property Counsel

The posting, as Spyre Therapeutics wrote it

Spyre Therapeutics is a clinical-stage biotechnology company committed to developing next-generation therapies that elevate the standard in immunology by delivering more complete disease control, greater durability, and a simpler treatment experience for patients. Spyre's pipeline includes investigational extended half-life antibodies targeting α4β7, TL1A, IL-23, and IL-17A/F as well as rational combination programs.

Role Summary

Spyre Therapeutics is seeking an experienced Senior Director, Intellectual Property Counsel, to develop and execute intellectual property strategies that support our pipeline and long-term business objectives. This individual will lead global patent portfolio development, prosecution, and risk assessment, partnering closely with Research, Development, CMC, Clinical, and Business Development. They will also be responsible for trade secret protection and support brand name creation and protection.

This role is intended for a senior IP leader who can become Spyre’s principal intellectual property counsel. The successful candidate will take increasing responsibility for setting company-wide IP priorities, advising executive leadership, and leading the IP function, with the potential to assume Chief Intellectual Property Counsel responsibilities, depending on business needs and performance.

This hands-on role requires strong scientific fluency, sound legal judgment, and the ability to translate complex intellectual property issues into practical recommendations, as well as leadership experience and budget management capability. The successful candidate will bring a combination of law firm and in-house biotechnology experience, with a proactive approach to protecting innovation in a growing organization. Experience should include advising senior business and scientific leaders, managing outside counsel and budgets, and making portfolio and risk-prioritization decisions tied to company objectives.

Key Responsibilities

IP Strategy and Portfolio Management

• Develop and execute global intellectual property strategies aligned with the company’s pipeline, research priorities, and corporate objectives.
• Build and manage patent portfolios covering drug candidates, formulations, manufacturing processes, methods of use, and other innovations.
• Draft, review, and oversee the preparation and prosecution of U.S. and international patent applications.
• Evaluate invention disclosures and partner with scientists to identify patentable discoveries and develop appropriate filing strategies.
• Identify and ensure protection of trade secrets.
• Conduct and oversee freedom-to-operate, patentability, validity, and infringement analyses; communicate findings and recommend approaches to address identified risks.
• Support life cycle and exclusivity planning, including patent term extension opportunities and coordination with Regulatory and other relevant functions.
• Monitor competitor patent activity and emerging intellectua

[…]
k in a fast-paced, dynamic environment where you help shape the culture of our young company, contribute broadly to advance meaningful medicines, and learn quickly.

• Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits.
• Unlimited PTO
• Two, one-week company-wide shutdowns each
• Commitment to provide professional development opportunities.
• Remote working environment with frequent in-person meetings to address complex problems and build relationships.

The expected salary range offer for this role is $320,000 to $336,000. Actual pay offered may vary depending on job related knowledge, experience, education, and geographic location.
As an equal opportunity employer, Spyre is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job-related characteristics or other prohibited grounds specified in applicable federal, state and local laws. We also embrace differences in experience and background, and welcome diversity of opinions and thought with active recruitment designed to create a stronger and better Spyre that is focused on developing life-changing products for patients.

Spyre Therapeutics, along with other biotech companies, has become aware of a surge in email scams targeting prospective job candidates within our industry. Please be aware that official recruiters at Spyre Therapeutics only use email addresses with the domain “@spyre.com.” We want to also emphasize that we never request candidates to make any purchases or divulge sensitive personal information via email.

Please also be aware that all job postings will be listed on our website at spyre.com/careers/.