Associate Director, Medical Affairs

The posting, as Xenon Pharmaceuticals wrote it

Who We Are

Xenon Pharmaceuticals (NASDAQ:XENE https://www.nasdaq.com/market-activity/stocks/xene) is a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development, and commercialization of life-changing therapeutics for patients in need. We are looking for great people who thrive in a respectful, collaborative, inclusive, and productive culture to join the Xenon team.

What We Do

We are advancing an exciting product pipeline https://xenon-pharma.com/pipeline to address indications with high unmet medical need, including epilepsy, depression and pain. Our Phase 3 azetukalner program represents the most advanced, clinically validated potassium channel modulator in late-stage clinical development for multiple indications. In March 2026, we announced positive topline data from our Phase 3 X-TOLE2 study of azetukalner in focal onset seizures (FOS), and we submitted a New Drug Application to the Food and Drug Administration in the third quarter of 2026. Our Phase 3 epilepsy program also includes a second FOS study, X-TOLE3, which would support regulatory submissions outside the U.S., and the X-ACKT study in primary generalized tonic-clonic seizures, which would support regulatory submissions for an additional epilepsy indication. We also have multiple Phase 3 azetukalner clinical trials underway in major depressive disorder (MDD) and bipolar depression (BPD), based on topline data from our Phase 2 X-NOVA clinical trial. In addition, we are proud of our strong heritage in human genetics, deep understanding of ion channel biology, and expertise in novel chemistries to enable potent, selective ion channel targeting. We continue to advance an early-stage pipeline of novel therapeutic candidates, including Phase 1 studies for XEN1701 and XEN1720 (targeting Nav1.7) and XEN1120 (targeting Kv7), which are being developed for pain. Backed by a strong balance sheet to support our growth plans, we continue to build a fully integrated, premier neuroscience company with strong discovery, clinical development, corporate, and commercial operations.

About the Role

To be successful in this role, you will bring strong scientific acumen and a passion for adult learning, translating complex clinical and mechanistic concepts into clear, practical learning experiences. You will partner closely with Medical Directors and cross-functional stakeholders to develop and maintain KIQs, core talking points, objection-handling resources, and other enablement tools, and lead onboarding and ongoing medical training for new hires and existing teams. You will also help translate scientific literature and field insights into training priorities and actionable medical initiatives, contributing to integrated medical planning within your areas of responsibility. You will also support the Medical Directors in congress execution, training, insights-to-action, tiering, and literature alerts. Reporting directly to the Executive Director, Medical
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ce in Medical Affairs, Medical Education, Scientific Communications, or related functions.

• Experience developing and delivering training for multiple audiences (e.g., field medical, congress teams, cross-functional stakeholders), with demonstrated ability to translate complex data into clear, practical learning.
• Strong instructional design and facilitation skills (live and virtual), including building curricula, developing modules, and using feedback/metrics to continuously improve training effectiveness.
• Excellent interpersonal and stakeholder management skills; ability to build credibility and partner effectively with Medical Directors, Scientific Communications, Commercial Training, and Compliance.
• Demonstrated project management skills with the ability to prioritize, deliver on timelines, and manage training programs alongside broader Medical Affairs initiatives in a fast-paced environment.
• Experience supporting medical congress planning, field insights synthesis, advisory boards, or related medical strategy initiatives preferred; ability to translate scientific literature and insights into strategic recommendations and educational priorities.
• Strong written and verbal communication skills with high attention to scientific accuracy and a compliance-first mindset in content development and delivery.

Our Total Rewards program includes base salary, target bonus, and stock options, as well as a full range of benefits including medical, dental, vision, short-& long-term disability, accidental death & dismemberment, and life insurance programs, Employee Assistance Program, travel insurance, and retirement savings programs with company matching contributions.

Xenon encourages time to rest and re-charge through vacation, personal days, sick days, and an end-of-year company shutdown. Xenon highly values employee development and has an expanding Training, Learning & Development program, including a Tuition Assistance program for advanced degrees.