Scientist II, CMC Pipeline Innovation

The posting, as Legend Biotech US wrote it

Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy through a portfolio of innovative technologies, including autologous, allogeneic, and in vivo cell therapy approaches. Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of serious diseases. From our global network of research and development sites, we are committed to discovering and developing safe, effective, and cutting-edge therapies for patients worldwide.

Legend Biotech entered into a global collaboration agreement with Johnson & Johnson to jointly develop and commercialize CARVYKTI® (ciltacabtagene autoleucel; cilta-cel). Through this strategic partnership, we combine complementary expertise and capabilities to advance innovative immunotherapies for patients living with multiple myeloma.

Legend Biotech is seeking a Scientist II, CMC Pipeline Innovation as part of the Technical Development team based in Somerset, NJ.

Role Overview

The Scientist II, CMC Pipeline Innovation plays a key role in advancing innovative manufacturing, analytical, and characterization technologies that accelerate the development of cell and gene therapies. This position is responsible for the hands-on execution of process and analytical studies aimed at improving process understanding, product characterization, quality, scalability, speed, and cost efficiency across the development pipeline.

Working closely with cross-functional teams, the Scientist II generates scientific and technical data to evaluate emerging technologies, advance technology readiness milestones, and support implementation decisions. The role is expected to communicate innovation outcomes, provide data-driven recommendations, and facilitate the transfer of successful technologies into development and manufacturing. Through rigorous experimentation, data analysis, and a commitment to continuous improvement, the Scientist II helps deliver robust, scalable, and innovative solutions across cell and gene therapy platforms.

Key Responsibilities

• Execute lentiviral vector (LVV) downstream process development activities, including the design, optimization, and scale-up of purification processes utilizing chromatography-based and alternative separation technologies. Responsibilities include hands-on development of capture and polishing strategies employing affinity, ion exchange, size-exclusion, hydrophobic interaction, membrane chromatography, and other purification approaches to improve vector recovery, purity, scalability, and manufacturability.
• Develop and execute proof-of-concept, feasibility, and characterization studies to assess new technologies and generate data-driven recommendations for further development, implementation, or di

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t- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide voluntary commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs; demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work.

Pay Range (Base Pay)

$110,706 — $145,303 USD

Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.

Work Authorization & Employment Eligibility

Applicants must be authorized to work in the United States. As part of our commitment to maintaining a lawful workforce and ensuring compliance with federal employment regulations, we participate in the E-Verify program. If you are selected for employment, you will be required to complete the Form I-9 process, and your employment eligibility will be verified through E-Verify in accordance with applicable federal law. We are committed to providing a fair, transparent, and welcoming hiring experience for all candidates.

EEO Statement

It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.

Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.

For information related to our privacy notice, please review: Legend Biotech Privacy Notice .