Senior Manager, Evidence & Insights (RWE & HEOR)

The posting, as Real Chemistry wrote it

At Real Chemistry, making the world a healthier place isn’t just an aspiration—it’s our everyday reality. Our drive to transform healthcare is informed by our blend of deep scientific expertise, human-centred creativity, and AI-driven insights, fostering a unique environment where innovation thrives and our people are impact-obsessed. As a global agency, we provide a full suite of services across healthcare communications and marketing to our clients, including top players in the pharmaceutical and biotech industries.

Our #LifeatRealChem culture is rooted in our people—we believe we are best together and are committed to excellence for both our clients and colleagues. Whether you're a seasoned professional or just starting your career, if you share our passion for healthcare and connection, we invite you to explore our opportunities.

Discover your purpose. Embrace innovation. Experience #LifeatRealChem.

Real Chemistry is looking for an Senior Manager join our growing Evidence & Insights team!

The Senior Manager, Evidence & Insights provides strategic and scientific support across real-world evidence (RWE), health economics and outcomes research (HEOR), and evidence generation. This role co-leads client engagements end-to-end, helping to shape evidence strategies, oversee analytics and deliverables, and advise biopharma and related stakeholders.

This is a hybrid role, based in any of our US offices—including New York City, Boston, Chicago, Indianapolis, or San Francisco—or remotely within the US, depending on team and business needs.

What you'll do

• Co-lead and support RWE and HEOR strategy across client programs, including evidence planning, study design, and interpretation of findings to inform value, access, and payer and health system decision-making.
• Design and support evidence generation plans (e.g., RWE studies, retrospective database studies, economic models) aligned to product lifecycle needs and client requirements.
• Develop and oversee the process for systematic literature reviews (SLRs), including the development of study protocols, execution of study searches, delegation of screening, and oversight of data extraction and reporting (leveraging the Nested Knowledge platform where possible).
• Translate complex real-world datasets and outcomes evidence into clear, defensible insights and recommendations for clients (clinical, economic, and utilization outcomes).
• Serve as a client co-lead alongside Director and VP: build trusted relationships, guide strategic direction, and ensure work products meet scientific rigor, timelines, and client expectations.
• Directly manage staff planning, internal and external project timelines, internal and external communications, and budgets to ensure projects are adequately staffed, managed, and executed.
• Stay current on evolving evidence standards and trends impacting access decisions, including:
• HTA requirements and value frameworks
• Payer evidence expectations and compa

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recruiter will discuss the specific expectations for the role you're pursuing during the interview process and keep you informed throughout the hiring journey. For employees located within a one-hour commute of a Real Chemistry office, we require in-person attendance two days per week, either from a Real Chemistry office or when working onsite with clients. Employees in regions without a nearby office may work remotely and come together throughout the year for collaboration, culture-building, learning, and team connection opportunities. While these guidelines reflect our current workplace model, we understand that everyone’s circumstances are unique. If you require additional flexibility, we welcome an open conversation with your recruiter and our HR team to discuss your needs and determine what may be possible.

Real Chemistry is an Equal Opportunity employer. We continually strive to build and sustain an inclusive and equitable work environment where our employees feel empowered to leverage all they bring from their personal lived experience and professional expertise, to make our team the best in the industry. We encourage motivated and qualified applicants to apply without regard to race, color, religion, sex (including pregnancy), sexual orientation, gender identity/expression, ethnic or national origin, age, physical or mental disability, genetic information, marital information, or any other characteristic protected by federal, state, or local employment discrimination laws where Real Chemistry operates. Should you require accommodations throughout the interview process please let your recruiter know.

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