Director, GI Forecasting

The posting, as Revolution Medicines wrote it

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity

Reporting to the Senior Director, U.S. Forecasting, the Director, U.S. Forecasting will be responsible for developing and executing forecasting models and analyses that support product strategy, performance management, and operational planning.

This role focuses on building and maintaining short-term demand forecasts and patient-based models across U.S. oncology assets, enabling manufacturing, supply chain, and commercial decision-making. The Director will partner closely with cross-functional stakeholders to align on forecast inputs, assumptions, and outputs, while ensuring high-quality, timely deliverables.

As a key contributor within the U.S. Forecasting function, this individual will execute forecasting processes in alignment with the broader U.S. forecasting strategy and contribute to ongoing improvements in forecasting capabilities, tools, and data integration.

This position is based at our Redwood City, CA headquarters, with flexibility for remote candidates willing to travel regularly to the office.

Responsibilities include

Develop, maintain, and refine short-term demand forecasts across U.S. oncology products, including SKU-, dose-, and channel-level projections to support supply chain and commercial planning.

Build and manage patient-based forecasting models incorporating oncology-specific dynamics such as incidence, biomarker segmentation, lines of therapy, treatment duration, and market evolution.

Conduct scenario, sensitivity, and risk analyses to evaluate key business drivers and inform near-term decision-making.

Translate complex data, assumptions, and model outputs into clear, actionable insights to support launch planning, performance tracking, and operational readiness.

Partner cross-functionally with Commercial, Finance, Market Access, Medical Affairs, Supply Chain, and Manufacturing to gather inputs, validate assumptions, and ensure alignment on forecast outputs.

Support development of production and inventory strategies by providing accurate and timely forecast updates and analyses.

Integrate real-world data, secondary data sources (e.g., IQVIA), and competitive intelligence into forecasti
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anges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

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Base Pay Salary Range
$211,000 — $264,000 USD

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