Principal Product Manager, Chemistry

The posting, as Revolution Medicines wrote it

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity

We are seeking a Principal Product Manager, Chemistry to deliver products and capabilities that help Chemistry teams make faster, higher-confidence design and progression decisions in oncology-focused drug discovery.

This role will define and deliver the product strategy for Chemistry workflows, data products, and AI-enabled decision support using the right mix of internal product development, SaaS platforms, vendor partnerships, integrations, and RevCore capabilities. You will partner with medicinal chemists, synthetic chemists, computational chemists, analytical chemists, DMPK and Biology partners, Data Science, ML Engineering, Data Engineering, IT, and platform teams to turn complex Chemistry workflows into intuitive, scalable solutions that accelerate the Design-Make-Test-Learn cycle.

Own Chemistry product strategy

Define the vision and roadmap for Chemistry products and capabilities across medicinal chemistry, synthetic chemistry, analytical chemistry, compound management, and the Design-Make-Test-Learn cycle.

Build a Now, Next, Later roadmap from foundational compound data capabilities to self-service analytics, model-supported design, and AI-enabled decision support.

Set success metrics tied to trusted compound data access, reduced manual data preparation, faster design cycles, compound progression decisions, and scientific adoption.

Shape product solutions around Chemistry workflows and decisions

Understand workflows for medicinal chemists, synthetic chemists, computational chemists, analytical chemists, compound management teams, and cross-functional program teams.

Design solutions around key decision moments such as compound design, analog selection, route selection, synthesis planning, SAR interpretation, multi-parameter optimization, compound triage, and program prioritization.

Translate Chemistry workflows into clear product requirements, evaluation criteria, user stories, and prioritized capabilities.

Determine when to build, buy, partner, or integrate based on user needs, market capabilities, scalability, differentiation, interoperability, and long-term maintainability.

Establish trusted, reusabl
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anges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy . For additional information, please contact privacy@revmed.com .

Base Pay Salary Range
$211,000 — $264,000 USD

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