Scientist II, Biomarker Sciences/Translation Sciences

The posting, as Revolution Medicines wrote it

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity

As a Scientist II, Biomarker Sciences/Translational Sciences, you will be a key member of the Translational Research team, applying computational approaches to derive biological and translational insights from complex preclinical and clinical datasets. You will:

Translational Science: Apply computational approaches to uncover biomarkers, mechanisms of drug response and resistance, pharmacodynamic effects, and therapeutic strategies across translational studies.

Omics & Integrated Biology: Analyze and integrate bulk and single-cell sequencing, spatial transcriptomics, and other molecular data with biomarker, pathology, and efficacy/response outcomes to generate actionable biological hypotheses.

Scalable Analytics: Develop reproducible analytical workflows and partner on AI-enabled solutions that accelerate exploratory data analysis, visualization, and biological interpretation.

Cross-functional Collaboration: Partner across Translational Research, Translational Medicine, Discovery, Bioinformatics, and Information Sciences to address key scientific questions across the portfolio.

Analyze and integrate multimodal molecular and phenotypic datasets from translational studies to identify biomarkers, pharmacodynamic effects, mechanisms of response and resistance, and combination hypotheses.

Perform cross-study analyses to identify reproducible biological signals and translate computational findings into testable mechanistic and translational hypotheses.

Partner with experimental scientists on study design and testing of computationally derived biological hypotheses.

Partner with Biomarker Assays teams to translate insights into actionable biomarker analytes.

Partner with data science and technology teams to translate scientific needs into scalable analytical and visualization solutions.

Evaluate and apply emerging AI/ML approaches to accelerate analysis, data integration, and biological insight generation.

Clearly communicate complex analyses and biological conclusions to multidisciplinary project teams and scientific leadership.

Required Skills, Experience and Education

PhD in Cancer Biology, Molecular O
[…]
anges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

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Base Pay Salary Range
$132,000 — $166,000 USD

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