Senior Manager, Sample Management

The posting, as Revolution Medicines wrote it

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity

Provide direct, hands-on leadership to sample management staff, including daily work assignment, prioritization, and real-time problem solving.

Lead and participate in core sample management activities, including sample receipt, storage, tracking, retrieval, and disposal.

Ensure smooth day-to-day operation of automated storage systems, LIMS, and supporting laboratory infrastructure.

Train, mentor, and develop staff through on-the-job coaching, feedback, and performance management.

Develop, maintain, and enforce SOPs and best practices for all critical sample management processes.

Identify and implement process improvements to enhance efficiency, reliability, and scalability.

Serve as the primary point of contact for cross-functional partners, ensuring timely and accurate delivery of materials.

Work closely with the Director of Sample Management to communicate capacity, risks, and resource needs.

Support onboarding and ramp-up of new staff and technologies within the laboratory.

Provide technical leadership and subject matter expertise in tissue culture, including aseptic technique, routine cell line maintenance, culture optimization, cryopreservation, thawing, and recovery.

Lead the design and execution of fit-for-purpose cell banking strategies, including the creation, expansion, characterization, qualification, release, use, and retirement of research, master, and working cell banks.

Plan and oversee cell bank expansion activities, including seed-train design, passage management, scale-up scheduling, resource allocation, and assessment of growth, viability, and recovery performance.

Establish and maintain cell bank inventory controls that ensure unique identification, accurate storage locations, complete metadata, chain of custody, inventory reconciliation, capacity planning, and full lifecycle traceability.

Define and enforce contamination-control practices for tissue culture operations, including segregation strategies, biosafety requirements, cleaning and disinfection procedures, and appropriate response to contamination events.

Oversee cell bank quality assessments, including cell ident
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anges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

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Base Pay Salary Range
$164,000 — $205,000 USD

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